Hyperthermia in oncology

Hyperthermia can be an essential part of treatment for many types of cancer.

When hyperthermia is the only form of treatment, the results are between 13 and 30 percent better than when no form of therapy is used.

In combination with another treatments, hyperthermia can produce between 30 and 50 percent better results versus a patient who does not get hyperthermia. Think of radiotherapy, chemotherapy, or immunotherapy and hormone therapy. This applies to both curative and palliative treatment. In addition, there are very little side effects. (More information can be found on the Cancer page of this website).

In previous years, we have achieved remarkably good results, for example in whether or not metastatic or recurrent breast cancer, (colon) cancer, cervical cancer, ovarian cancer, lung cancer, pancreatic cancer, neck tumors, sarcomas, melanomas, bladder cancer, prostate cancer and other cancers.

Effects of Hyperthermia

In hyperthermia, the temperature of the body, in whole or in certain places, is increased to 40 ° C-44 ° C by means of (electromagnetic) radiation.

This has a number of consequences:

  • The blood flow of a tumor is usually defective. As a result, the effectiveness of chemotherapy (low concentration of the drugs in the tumor) and radiation (low-oxygen environment) is less than desired. Hyperthermia improves blood circulation to the tumor (s) and metastases, thus increasing the effectiveness of chemotherapy, hormone therapy and radiation.
  • Hyperthermia increases the concentration of certain proteins (HSP – Heat Shock Proteins). These proteins stimulate the immune system to attack cancer cells more effectively and also make them more sensitive to the body’s natural defenses.
  • The membrane of the cancer cell is softened by the heat (permeability), so that medicines can better penetrate into the tumor.
  • Cancer cells are killed or damaged by the heat and radiation. Healthy cells are not affected, unlike other forms of radiation (such as X-rays), which can also affect healthy cells.
  • Hyperthermia prevents damaged DNA from cancer cells (damaged by chemotherapy or radiation) from repairing, making the treatments more effective.
    Hyperthermia as a treatment is usually used in cancer, read more about this at: hyperthermia in cancer


There are various devices with which local hyperthermia treatments are given. These can mainly be divided into:

Radiative systems

Capacative systems

Oncotherm EHY 2000

Oncotherm EHY 2000
Oncothermia – Oncothermia

The temperature is not the only important, but also at the Specific Absorbance Rate of the heat (SAR) and the side effects of generating the heat

At the Hyperthermia Center we work with both types of systems, in order to arrive at the best treatments in combination. This allows us to not only reach the right temperature, but also provide a comfortable treatment.